Yes, you can run ads on specific days or times via the Review Your Campaign Settings screen.
You may want your ad to show whenever a customer searches online. Or perhaps you only want to show your ad on certain days, or during business hours when you’re there to handle customer inquiries. You can specify certain hours or days of the week when you want your ads to show.
By default, your Google Ads campaigns are set to show ads “All day.” This means your ads are eligible to appear throughout each calendar day. Keep in mind that if no one searches for your keywords at the specified time or day you scheduled, your ads are not going to show.